Page 53 - Book of Abstracts
P. 53

5 International Scientific Online Conference   DOI: https://doi.org/10.15414/2021.9788055224015

            th

             OSMOTIC RESISTANCE OF ERYTHROCYTES OF DIFFERENT BLOOD GROUPS UNDER THE
                               INFLUENCE OF CHAMERION ANGUSTIFOLIUM (L.) SCOP.
                                                                2
                                                                                 2
                                       1
                    Kateryna Garkava , Ulyana Tymoshenko ,Raisa Pavlyuk ,Irina Michailova
                                                                                                     1
                         1 National Aviation University, Kyiv, Ukraine; E-mail.: immunolog@ukr.net
                2 Government Agency «Institute of Hematology and Transfusiology National Academy of Medical
                                             Sciences of Ukraine» Kyiv, Ukraine
                  In recent decades, scientists have looked at the link between blood types and the risk of
             developing certain diseases. Thus, it is believed that people with blood group 0 (I) are more prone
             to the peptic ulcer of the stomach and duodenum, gastritis as well as hip dysplasia. Persons with
             A (II) – to obliterating atherosclerosis, endarteritis of the lower extremities, rheumatic diseases,
             coronary heart disease, bronchial asthma, allergies, leukemia, cholecystitis, and gallstone disease.
             Carriers  of  the  B  (III)  group  are  more  likely  to  suffer  from  pneumonia,  radiculitis,  and  joint
             disease. Individuals with AB (IV) blood type are prone to SARS, sore throat, sinusitis, and heart
             disease. Almost all of these diseases are based on erythrocyte dysfunction.
                  The use of medicinal plants to replenish the body with biologically active compounds to
             improve its adaptive capacity is necessary and timely in current days. Chamerion angustifolium
             (L.) Scop., which has antitumor, anti-inflammatory, and antianemic properties, attracts special
             attention. In this regard, this study aimed to investigate the effect of Chamerion angustifolium on
             the osmotic resistance of erythrocytes of different blood groups of donors.
                  To reduce the destruction of erythrocytes, they were treated with 0.1 % water-salt extract
             from Chamerion angustifolium. To obtain a water-salt extract a solution of 0.15 mol/L NaCl was
             used.  Erythrocyte  resistance  was  determined  by  the  percentage  of  hemolysis  in  buffered
             isotonic sodium chloride solutions of different concentrations from 1.0 to 0.1 % after treatment
             with the test plant.
                  Erythrocyte membranes were a model for studying the level of free radical processes, the
             state of the body's antioxidant systems, and its adaptive capabilities. The erythrocytes that
             were not treated with the test plant were the control group.
                  The  results  showed  that  Chamerion  angustifolium  increased  the  osmotic  resistance  of
             erythrocytes 0 (I) of blood group by 28 %, A (II) by 56 %, and B (III) by 35 %.
                   Thus,  the  osmotic  resistance  of  erythrocytes  A  (II)  blood  group  was  higher  by  29  %
             compared with 0 (I) blood group and 21 % compared with B (III) blood group, indicating a
             higher tropism of Chamerion angustifolium to erythrocytes A (II) groups, than to 0 (I) and B (III)
             blood groups. Due to this fact, the individual need, taking into account also blood groups, the
             use of medicinal plants to improve the adaptive capacity of the organism is beneficial.
            Keywords: Chamerion angustifolium, blood groups, erythrocytes, medicinal plants.

















             5 International Scientific Conference Agrobiodiversity for Improving the Nutrition, Health, Quality of Life and  |52
              th
                                               Spiritual Human Development
                                                                                                          November 3  2021
                                                              rd
   48   49   50   51   52   53   54   55   56   57   58